The objective of this ongoing study is to investigate how abundance, distribution, and activity of mammals (>= 1 kg) vary across grassland to shrubland ecotones in the northern Chihuahuan Desert. This dataset includes animal occurrence data derived from camera trap images captured in 24 grassland-to-shrubland ecotone sites in the Jornada Basin, Dona Ana County, New Mexico, USA. The data set contains occurrence records from 14 mammal species with the date and time a species was detected. Also included are the number of individuals in a photo, operational dates and number of functional camera days for cameras, total number of trap nights a camera was active, and geographical coordinates of camera trap locations. Sampling is ongoing and occurs during the monsoon season from July-November. Sampling has occurred annually since 2014.